The Cougars will play the Blue Devils on Saturday, April 5th, 2025. Your timezone's tip off time is 7:49 pm CDT. Check local listings or your nearest streaming app for coverage.
Review our College Basketball Betting guide to learn how to bet this game.
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Table of Contents
- Matchup Stats
- Moneyline Mage
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
The 2024-25 college basketball postseason has arrived. With tournament action on the docket, Houston and Duke are set to tip-off on Saturday, April 5th, 2025. Here's your chance to partake in March Madness! The end of the regular season has left us with solid trends for each team. Use the following performance insights and stats to handicap what promises to be an exciting matchup.
- SportsBetting3.com Power Rankings - Houston wound up with a 100.00 SportsBetting3.com conference power ranking for the 2024-25 college basketball regular season, while Duke finished with a 100.00 power ranking.
- Away Records - Tournament games are typically played at neutral venues, which means both teams are away from their home courts. Houston comes to this matchup with a 10-0 record as an away team, ranking them 1st in the Big 12 Conference for away team wins. Their opponent, Duke, finished the regular season with a 10-1 record as an away team, ranking them 1st in the ACC Conference for away team wins.
- Conference Win Percentage - Houston finished 1st (0.950) in the Big 12 Conference, with Duke ending up 1st (0.950) for their conference win percentage in the 2024 ACC Conference.
- Overall Win Percentage - Houston had a 0.895 regular season overall win percentage, with Duke notching a 0.921 overall win percentage at the end of the 2024-25 regular season.
- Team Records - Houston tallied a 34-4 regular season overall record. Meanwhile, Duke put together a 35-3 standing for 2024-25 college basketball regular season.
Moneyline Mage
Spelling out the winners with humor since the middle ages.
Hocus pocus, Houston and Duke clash in March Madness magic on Saturday.
Houston 34-4 faces Duke 35-3 in a battle for the ages.
Both teams dominated with 19-1 conference records. Who will emerge victorious?
The tables below have the best point spread lines, total lines, and moneylines for this matchup. Bet on March Madness games at BetRivers and BetMGM. Review this matchup's prop bets below. May the best wizard win!
Best Cougars at Blue Devils Odds
| Underdog Houston |
Favorite Duke |
|---|---|
| Over | Under |
|---|---|
| Underdog Houston |
Favorite Duke |
|---|---|
Matchup Odds FAQs
Duke is a -4.5 -110 point spread favorite at BetMGM, while Houston is a +5 -110 point spread underdog at BetRivers.
The best over line is 136.5 -112 points at BetRivers, which means you risk $112 to win $100 betting the over. The best under line is 136.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.
Duke is a -250 moneyline favorite at BetMGM and Houston is a +200 moneyline underdog at BetMGM.
College Basketball Odds Example
| Game |
 BetMGMBet |
|---|---|
|
Houston
Duke
4/05/25 7:49pm CDT
|
+4.5 -110-4.5 -110 |
Underdog Houston - Houston bettors risk $100 to win $90.91 at -110 odds.
A +4.5 Houston underdog bet wins if they lose by 4 or fewer, tie, or win outright. Your bet loses if they lose by 5 or more.
Favorite Duke - Duke bettors risk $100 to win $90.91 at -110 odds.
A -4.5 Duke favorite bet wins if they win by 5 or more. Your bet loses if they win by 4 or fewer, tie, or lose outright.
Houston at Duke Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
|
BetMGM Bet |
|
|---|---|
|
Houston
Duke
First to 5 Points
4/05/25 7:49pm CDT
|
+100-140Bet |
|
Houston
Duke
First to 10 Points
4/05/25 7:49pm CDT
|
+105-145Bet |
|
Houston
Duke
First to 15 Points
4/05/25 7:49pm CDT
|
+115-160Bet |
|
Houston
Duke
Game to Overtime
4/05/25 7:49pm CDT
|
Yes +800No -3000Bet |
Team Standings
| Team | W-L | Win% | Home | Away | Conf | CGB | Conf% | Strk |
|---|---|---|---|---|---|---|---|---|
| ACC | ||||||||
| #3 Duke | 35-4 | 0.897 | 17-0 | 10-1 | 19-1 | - | 0.950 | L1 |
| Big 12 | ||||||||
| #2 Houston | 35-5 | 0.875 | 16-1 | 10-0 | 19-1 | - | 0.950 | L1 |
Houston & Duke Futures Odds
Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the Final Four write-up.
Houston Championship Odds| Team |
BetMGM |
 BetRivers |
|---|---|---|
| Houston | +1100 Bet |
+1100 Bet |
| Team |
BetMGM |
BetRivers |
|---|---|---|
| Duke | +1300 Bet |
+1000 Bet |
Houston & Duke Team Pages
Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Houston vs Duke College Basketball Game
- Open a new sports betting before game time.
Review our list of sports betting sites. Open a new before the game starts on Saturday, April 5th, 2025 at 7:49 pm CDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
- Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Paypal.
- Tap to the sportsbook's College Basketball page, look for the Houston vs Duke Game.
Navigate to the sportsbook's College Basketball page. Next, look for live or matchups. Select the Houston vs Duke Game.
- Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your balance after the game.